Knockout of Cxcr3 in Mus musculus


Gene symbol Cxcr3
Gene name Chemokine (C-X-C Motif) Receptor 3
Gene entrez ID 12766
Gene aliases CKR-L2, CMKAR3, IP10-R, MigR, CD183
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol CXCR3
HUGO gene ID 4540
Gene entrez ID 2833
Genecards CXCR3


Intervention Knockout
Genetic background FVB/N
Wound model Full-Thickness Excisional Punch
Wound Dimensions 20 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Thick keratinized scar with a thickening of both the epidermis and dermis; the dermis was disorganized with thick and long collagen fibrils and contained excessive collagen content; Pesented lower tensile/burst strength
References Yates et al. 2009
Yates et al. 2010

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.