Knockout; overexpression of Egr1 in Mus musculus


Gene symbol Egr1
Gene name Early Growth Response 1
Gene entrez ID 13653
Gene aliases TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol EGR1
HUGO gene ID 3238
Gene entrez ID 1958
Genecards EGR1


Intervention Knockout; overexpression
Genetic background C57BL/6
Wound model Full-Thickness Incision
Wound Dimensions 30 mm
Wound Location Dorsum
Effect on skin wound healing Knockout: Impaired wound healing; overexpression: exuberant tissue repair, with enhanced collagen accumulation and increased tensile strength of incisional wounds
References Bryant et al. 2000
Wu et al. 2009

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.