| Intervention | Protein administration |
| Genetic background | SKH-1-hr |
| Wound model | Skin-Fold Chamber |
| Wound Dimensions | 5 mm^2 |
| Wound Location | Dorsum |
| Effect on skin wound healing | Single-high-dose treatment accelerated wound epithelialization and induced maturation of newly formed microvascular networks. In contrast, repeated-high-dose impaired the healing process, delayed re-epithelialization with a lack of maturation of microvascular networks |
| References | Sorg et al. 2009 |